Vitofyllin® 50 mg and 100 mg tablets
Film-coated tablets for dogs
Composition
- Propentofylline 50 mg per tablet.
- Propentofylline 100 mg per tablet.
Pharmacotherapeutic category
Peripheral vasodilator (purine derivatives).
Properties
Propentofylline increases blood flow of the heart, skeletal muscle and brain and therefore the oxygen supply. It has a modest positive chronotropic effect and a marked positive inotropic effect, anti-arrhythmic effect in dogs with myocardial ischemia and a bronchodilator action. It inhibits platelet aggregation and improves flow properties of erythrocytes. It has a direct effect on the heart and reduces peripheral vascular resistance thereby lowering cardiac load. Propentofylline may increase willingness to exercise and exercise tolerance, particularly in older dogs. After oral administration, propentofylline is fast and completely absorbed and quickly distributed into tissues.
Indications
For the improvement of peripheral and cerebral vascular blood circulation. For improvement in dullness, lethargy and overall demeanour in dogs.
Dosage, route and method of administration
Oral gavage: 3-5 mg propentofylline/kg BW, twice daily. Each cross-snap-tablet of 50 mg or 100 mg can be divided into equal halves and quarters.
| Tablet strength | Body Weight (kg) | Tablets | Daily total (tablets) | Daily total dose (mg/kg) | |
|---|---|---|---|---|---|
| Morning | Evening | ||||
| Vitofylline® 50 mg tablet | 2.5 - 4 kg | 1/4 | 1/4 | 1/2 | 6.3 - 10.0 |
| 5 - 7 kg | 1/2 | 1/2 | 1 | 7.1 - 10.0 | |
| 8 – 9 kg | 3/4 | 3/4 | 1 1/2 | 8.3 - 9.4 | |
| 10 - 15 kg | 1 | 1 | 2 | 6.7 – 10.0 | |
| 16 - 25 kg | 1 1/2 | 1 1/2 | 3 | 6.0 – 9.4 | |
| 26 - 33 kg | 2 | 2 | 4 | 6.1- 7.7 | |
| Vitofylline® 100 mg tablet | 20 - 33 kg | 1 | 1 | 2 | 6.0 - 10.0 |
| 34 - 49 kg | 1 1/2 | 1 1/2 | 3 | 6.1 – 8.8 | |
| 50 - 66 kg | 2 | 2 | 4 | 6.1 – 8.0 | |
| 67 - 83 kg | 2 1/2 | 2 1/2 | 5 | 6.0 – 7.5 | |
Shelf-life
3 years.
Packaging
Carton with 4 or 10 blisters with 14 tablets (56 or 140 film-coated tablets).
The trade name and/or the specifications of the product (target animal species, indications, dosage and administration, precautions and warnings, etc.) may differ from country to country. Please contact us for further information.