One tablet of 4.5 grams contains: Colistin sulfate eq. 3 000 000 I.U.
Intestinal antiinfectives (antibiotics: colistin).
Colistin (Polymyxin E) is an antibiotic belonging to the polymyxin group. The antibacterial action of polymyxins is based on a passive interaction with the bacterial cell wall. This implicates that polymyxins also are able to inactivate bacterial endotoxins. Colistin exerts concentration-dependent activity against Gram-negative bacteria (e.g. E. coli, Salmonella spp.). Following oral administration high concentrations are achieved in the gastrointestinal tract, i.e. the target site, due to the poor absorption of the substance.
For the treatment of enteric infections in calves caused by non-invasive E. coli susceptible to colistin.
Dosage, route and method of administration
Oral administration in calves: 5 mg colistin sulfate eq. 95 000 IU per kg BW or 1 tablet per 30 kg BW, once daily for 3 to 5 days. In calves of less than 48 hours, the daily dose should be divided over 2 administrations.
Carton with 4 or 20 blisters of 5 tablets (20 or 100 tablets).
The trade name and/or the specifications of the product (target animal species, indications, dosage and administration, precautions and warnings, etc.) may differ from country to country. Please contact us for further information.